2C-E (4-ethyl-2 5-dimethoxy) powder


2C-E (4-ethyl-2,5-dimethoxy) salt/powder:
2,5-Dimethoxy-4-methylamphetamine (2C-E) is a psychedelic and a substituted amphetamine. It was first synthesized by Alexander Shulgin, and later reported in his book PiHKAL: A Chemical Love Story.
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Minimum order quantity is: 1 grams


2C-E (4-ethyl-2,5-dimethoxy) powder

2C-E (4-ethyl-2 5-dimethoxy) powder is a psychedelic compound known for its hallucinogenic effects. Let’s explore its chemical structure and composition in more detail:

Molecular Structure of 2C-E

The molecular structure of 2C-E consists of a phenethylamine backbone with additional ethyl and dimethoxy functional groups attached at specific positions. These structural features contribute to its psychoactive properties and determine its interactions with neurotransmitter receptors in the brain.

Composition and Purity Considerations

The purity of 2C-E powder is essential for ensuring its safety and efficacy. Impurities or contaminants present in the compound can alter its effects and increase the risk of adverse reactions. Therefore, it’s crucial to obtain 2C-E from reputable sources that adhere to strict quality control standards and provide certificates of analysis to verify purity levels.

Effects and Pharmacology

2C-E powder exerts its psychoactive effects by interacting with serotonin receptors in the brain, particularly the 5-HT2A receptor subtype. This leads to alterations in neurotransmitter signaling pathways, resulting in profound changes in perception, mood, and cognition. The effects of 2C-E can vary depending on factors such as dosage, individual sensitivity, and environmental context.

Dosage and Administration

The dosage of 2C-E powder can vary significantly depending on factors such as the individual’s weight, tolerance, and desired level of effects. It’s crucial to start with a low dose and gradually titrate upwards to assess tolerance and sensitivity. The most common routes of administration for 2C-E include oral ingestion and insufflation (snorting).

Benefits and Potential Uses

While 2C-E is primarily known for its recreational use and psychedelic experiences, it also has potential therapeutic applications. Some research suggests that 2C-E may have antidepressant and anxiolytic properties, making it a subject of interest in psychiatric research. Additionally, some individuals use 2C-E for spiritual or introspective purposes, believing it can facilitate personal growth and insight.

Risks and Side Effects

Despite its potential benefits, 2C-E powder carries risks, especially when used irresponsibly or in excessive doses. Common side effects of 2C-E include:

  • Nausea and vomiting
  • Anxiety and paranoia
  • Increased heart rate and blood pressure
  • Hallucinations and sensory distortions
  • Potential for psychological distress or “bad trips”

Legal Status

The legal status of 2C-E varies from country to country. In some jurisdictions, it is classified as a controlled substance due to its potential for abuse and recreational use. It’s essential to research and understand the legal status of 2C-E in your location before purchasing or using it.


1. Is 2C-E safe to use? While 2C-E can be used safely when taken responsibly and at appropriate doses, it carries risks of adverse effects, especially at higher doses. It’s essential to research and understand the potential risks before using 2C-E.

2. How long do the effects of 2C-E last? The duration of 2C-E effects can vary depending on factors such as dosage and individual metabolism. Generally, the effects of 2C-E can last anywhere from 6 to 12 hours, with lingering effects possible for several hours afterward.

3. Can 2C-E be addictive? There is limited research on the addictive potential of 2C-E. However, like other psychedelics, it is not considered to be physically addictive. However, some individuals may develop a psychological dependence on its effects.

4. What precautions should I take when using 2C-E? When using 2C-E, it’s essential to start with a low dose, use it in a safe and comfortable environment, and have a trusted individual present as a “trip sitter.” Additionally, avoid mixing 2C-E with other substances, especially alcohol or other psychedelics.

5. Can 2C-E be detected in drug tests? Standard drug tests typically do not screen for 2C-E. However, specialized tests may be able to detect its presence in urine or blood samples. It’s essential to be aware of the detection window and potential legal implications of using 2C-E in jurisdictions where it is prohibited.


In conclusion, 2C-E (4-ethyl-2,5-dimethoxy) powder is a potent psychedelic compound with both recreational and potential therapeutic applications. While it can induce profound alterations in consciousness and perception, it also carries risks of adverse effects and legal considerations. By understanding its properties, effects, and risks, individuals can make informed decisions about its use and minimize potential harm.