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1. Name of the medicinal product
Ephedrine Hydrochloride 30mg Tablets
2. Qualitative and quantitative composition
Ephedrine hydrochloride 30mg
For excipients see 6.1
3. Pharmaceutical form
Tablet
White, circular tablets marked E30 on one face and CP on the reverse
4. Clinical particulars
Ephedrine tablets are indicated for the treatment or prevention of attacks of bronchospasm in asthma.
4.2 Posology and method of administration
| Adults | 15 – 60mg three times daily | |
| Children | under 1 year
1 – 5 years 6 – 12 years |
not recommended
15mg three times daily 30mg three times daily |
| Elderly | Dosage should be substantially reduced. Initial therapy should be 50% of adult dose. | |
4.3 Contraindications
Ischaemic heart disease
Hypertension
Thyrotoxicosis
Prostatic hypertrophy
Ephedrine has positive inotropic and chronotropic effects on the heart and its use should be avoided in patients with ischaemic heart disease.
Ephedrine increases blood pressure in man. Over the counter acquisition of sympathomimetics should always be considered in hypertensive patients whose blood pressure control has suddenly deteriorated.
Patients with hyperthyroidism may be susceptible to the effects of ephedrine. Ephedrine may precipitate acute urinary retention in patients with prostatic hypertrophy.
4.4 Special warnings and precautions for use
Ephedrine should be given with care to patients with hyperthyroidism, diabetes mellitus, angle-closure glaucoma and renal impairment.
Ephedrine has potentially life threatening effects in its acute cardiovascular and central stimulant effects.
Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.
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